A trio of senior Everton stars will feature for their respective countries and a host of the Club's young players are poised for action with their nations' youth teams during the forthcoming October international break.
Lucas Digne is aiming for Nations League success with France, who meet Belgium in Turin with a final spot against either Italy or Spain the prize for the winners.
Yerry Mina is due to contest three World Cup qualifiers with Colombia and Jordan Pickford and England are targeting a giant stride towards Qatar 2022 when they play a pair of qualifying matches.
Our guide below details when and where Everton's players will appear their countries, with all kick-offs shown in BST.
Wednesday 6 October
Lewis Dobbin: England U19 v France U19, Friendly, 3pm
Isaac Price and Sean McAllister: Northern Ireland U19 v Denmark U19, UEFA U21 Qualifier, 2pm
Luke Butterfield: Scotland U19 v Fleetwood Town, Friendly, 1pm
Thursday 7 October
Lucas Digne: France v Belgium, UEFA Nations League, 7.45pm
Yerry Mina: Uruguay v Colombia, FIFA World Cup 2022 Qualifier, Midnight
Jarrad Branthwaite: England U20 v Italy U20, Friendly, 7pm
Zan-Luk Leban: Slovenia U21 v England U21, UEFA U21 Qualifier, 7.15pm
Elijah Campbell, England U18 v Norway U18, Friendly, 3pm
Friday 8 October
Ryan Astley and Rhys Hughes: Slovenia U21 v Wales U21, UEFA U21 Qualifier, 3pm
Saturday 9 October
Jordan Pickford: Andorra v England, FIFA World Cup 2022 Qualifier, 7.45pm
Lewis Dobbin: England U19 v Mexico U19, Friendly, 2.30pm
Isaac Price and Sean McAllister: Czech Republic U19 v Northern Ireland U19, UEFA U21 Qualifier, 2pm
Luke Butterfield: Scotland U19 v Fleetwood Town, Friendly, 11am
Sunday 10 October
Lucas Digne, France v Italy or Spain, UEFA Nations League, TBC
Yerry Mina: Colombia v Brazil, FIFA World Cup 2022 Qualifier, 10pm
Monday 11 October
Jarrad Branthwaite: Czech Republic U20 v England U20, Friendly, 4pm
Zan-Luk Leban: Albania U21 v Slovenia U21, UEFA U21 Qualifier, 5.30pm
Elijah Campbell, England U18 v Russia U18, Friendly, 2pm
Tuesday 12 October
Jordan Pickford: England v Hungary, FIFA World Cup 2022 Qualifier, 7.45pm
Ryan Astley and Rhys Hughes: Holland U21 v Wales U21, UEFA U21 Qualifier, 7pm
Lewis Dobbin: England U19 v Belgium U19, Friendly, 3pm
Isaac Price and Sean McAllister: Northern Ireland U19 v Kazakhstan U19, UEFA U21 Qualifier, 2pm
Thursday 14 October
Yerry Mina: Colombia v Ecuador, FIFA World Cup 2022 Qualifier, 10pm
