Phil Jagielka and Seamus Coleman are out of Wednesday’s Merseyside derby but have not been ruled out of the FA Cup semi-final on Saturday.
In addition, Roberto Martinez will assess the fitness of Tom Cleverley, Aaron Lennon and Leighton Baines ahead of Tuesday evening’s training session.
The Everton manager said: "Phil Jagielka and Seamus Coleman will definitely be out of the derby but it is too early to make a final decision before the weekend.
“At this evening’s session we are going to assess Aaron Lennon, Tom Cleverley and Leighton Baines to have a final decision. They are very close and we will have a better idea if they are back for tomorrow.”
Tony Hibbert isn't ready for first team action yet after he played 45 minutes for the Under-21s on Monday night.
James McCarthy will be back in the squad after serving a one-match ban while Romelu Lukaku and Ross Barkley remain in the squad after starting on the bench last time out.
Martinez also explained that he would be comfortable turning again to young players if his injured personnel aren't ready to return this week.
He handed Callum Connolly and Tom Davies debuts last time out and is confident that the Club's burgeoning young talent would be ready to step in again if needed.
"I thought Tom Davies was very impressive and Callum Connolly showed his versatility," explained the boss. "They had that character to play in the first team and that is not an accident; we have that at the football club and it shows the programmes they are under to get them to that opportunity.
“If there are any minutes or places to be filled up by young payers we are in safe hands.”