Everton Under-21s face Villarreal at Goodison Park in the Premier League International Cup on Wednesday evening.
With the first-team in action at Chelsea, the Blues' second-string will simultaneously compete in their return to cup competition.
David Unsworth's side will be looking to make it back-to-back victories after securing a comfortable 3-1 win over Southampton in the Barclays Under-21 Premier League on Monday.
It will be the second game of the competition for the Toffees after they drew 1-1 with Celtic on matchday one.
Kick-off is 7pm, with admission free for Season Ticket holders and FOREVERTON members and £5 for adults and £3 for concessions otherwise.
Supporters unable to attend can follow match updates via Twitter here.