Roberto Martinez wants his players to take inspiration from their win at Manchester United when they attempt to end their Anfield hoodoo on Tuesday evening.
Bryan Oviedo’s late strike saw the Blues earn a first victory at Old Trafford in 21 years back in December.
The Toffees are aiming to terminate another unwelcome sequence of results at Anfield in their 222nd meeting against Liverpool.
Not since Kevin Campbell’s famous winner in 1999 have Everton taken maximum points from a trip across Stanley Park.
But Martinez says Everton will emerge from the dressing room with nothing to fear having proven already this season that they can match the best wherever they play.
“Before the game at Old Trafford and the Emirates there was a question whether we were mentally ready to be ourselves whatever the situation," he said. "I think we have proven we can be.
“The way we performed at the Emirates and the way we got the three points at Old Trafford shows that the team is ready to go anywhere and impose themselves.
“Those are the games that if you want to achieve big things, you need to enjoy them and embrace them. If you are not going to enjoy those games, you are not going to be at your best.
“But you need to remember that Liverpool are a really good side and they have an attacking threat, so that will make for an open game. From that point of view, it’s about making sure we are as good as we can be on the day and go there with nothing to fear."
Fourth-placed Liverpool currently occupy a one-point advantage over Everton but an away win would catapult the Blues back into the Champions League qualification positions.
Martinez says the proximity of the teams in the league standings is just another added element to what he believes will be yet another fascinating all-Merseyside contest.
The two sides played out a six-goal thriller in the corresponding fixture at Goodison Park in November – a game considered by many to be the most entertaining meetings in recent years.
“Normally in derbies you have got a team that has got a bigger need than the other to win for whatever reason,” said Martinez. “Now it is not the case because we are going into a Merseyside derby where there are two teams with a similar amount of points, both having good moments in the season and both still in the FA Cup.
“It is a game that has got every single ingredient to be important and then, on top of that, everyone knows the meaning of the Merseyside derby.
“The fans are excited and somehow it’s one of those games that we have to be able to enjoy, because it’s not just a derby for bragging rights. We are also competing for three crucial points.
“They have got history in their favour if you look at what has happened over the years, but it’s time for us to have enjoyment out of a performance and make sure that every Evertonian is proud.
"That’s the only focus that matters to me - to go to Anfield and be ourselves and give everything that we have to get a positive result.”
Everton return to Goodison Park on 1 February against Aston Villa. Click here to book tickets online.