Everton are unbeaten in their last five away games in all competitions and travel to St Mary's for the first time in seven years for Monday night's live game against Southampton.
David Moyes' side ran out 3-1 winners over the newly-promoted Saints at Goodison Park last September and are even money with Paddy Power to pick up all three points and do the double over the South Coast outfit, who surprisingly replaced Nigel Adkins with Mauricio Pochettino this week.
Despite trailing to an early Gaston Ramirez strike, the Toffees had the game wrapped up 3-1 by half time and are 21/10 with Paddy Power to be leading at half-time and full-time against the Saints on Monday night.
The Toffees are 17/2 to come from behind and win with Paddy Power while a repeat of the 3-1 scoreline is 13/1.
Leon Osman and Nikica Jelavic (twice) hit the net for Everton in the corresponding fixture and are 12/1 and 11/2 respectively to get the opening goal of the game as the Blues look for their fifth win in 12 away games this season.
England international Osman to score at anytime over the 90 minutes and Everton to win 3-1 is 6/1 in Paddy Power's Wincast betting while Jelavic to score at anytime and Everton to win is 11/4 in the same market.
Everton to score exactly three goals is now trading at 9/2.
Club captain Phil Neville celebrates his 36th birthday on Monday and is 33/1 to mark the occasion by scoring the first goal or 11/1 to score at anytime in the game.
Jelavic has scored six times in the Barclays Premier League this season and is just two behind Everton's leading scorer Marouane Fellainai.
The Belgian international is 13/2 to hit the net at St Mary's or 4/1 to score first for the Toffees.
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