David Moyes has made six changes to the Everton side to face Leeds United.
Young Portuguese midfielder Francisco Junior is handed his senior Blues debut, while there is also a first start for Bryan Oviedo.
Other players drafted into the starting XI are Sylvain Distin, Magaye Gueye, Steven Naismith and Jan Mucha.
Seamus Coleman continues at right-back after stepping into the role last time out, with Victor Anichebe hoping to build on the two goals he's scored in his last two outings.
There's good news on the subs' bench where Nikica Jelavic takes his place after missing the win over Swansea with a knee problem.
Further reinforcements are available in the form of Steven Pienaar, Leighton Baines, Phil Neville, Phil Jagielka, Leon Osman and Tim Howard.
Everton: Mucha, Coleman, Oviedo, Distin, Heitinga, Junior, Fellaini, Mirallas, Naismith, Gueye, Anichebe. Subs: Howard, Neville, Duffy, Jagielka, Jelavic, Vellios, Pienaar.