Johnny Heitinga starts his first league game of the season as Everton take on Swansea at the Liberty Stadium.
The Dutchman is recalled at the expense of Sylvain Distin and partners Phil Jagielka at the heart of the defence.
Phil Neville switches to right back to replace the injured Tony Hibbert with Leighton Baines at left back.
Seamus Coleman comes into midfield along with Leon Osman, Marouane Fellaini, Steven Pienaar and Kevin Mirallas.
Victor Anichebe replaces the injured Nikica Jelavic up front.
Bryan Oviedo is included in a matchday squad for the first time and is named on the bench. He is joined there by Jan Mucha, Steven Naismith, Magaye Gueye, Apostolos Vellios, Shane Duffy and Distin.
EFC: Howard, Neville, Baines, Heitinga, Jagielka, Coleman, Osman, Pienaar, Fellaini, Mirallas, Anichebe. Subs: Mucha, Naismith, Gueye, Vellios, Duffy, Distin, Oviedo
Swansea: Vorm, Rangel, Tate, Williams, Davies, De Guzman, Ki, Michu, Routledge, Pablo, Graham. Subs: Tremmel, Tiendalli, Monk, Dyer, Britton, Shechter, Moore