David Moyes is hoping to take advantage of Stoke's 'big year' on Tuesday night.
The Potters will be playing their 54th match of the season, thanks largely to a European campaign which began with a Europa League qualifier in July.
Everton have played 44 games this season and are now second in the Premier League form table.
"I think nowadays it does," said a cautious Moyes in response to a question about the workload taking its effect on Tony Pulis' squad. "Because players think about the number of games they have had. But these are the questions for Tony, I can only answer questions about Everton.
"I think it has been a long year for Stoke. European football was a great achievement for them, on the back of an FA Cup final last year. They have had a big year; this was always a big season for them because of the European games - I think they have had a good year."
The Potters have developed a reputation for being astute exponents of the more physical side of the game and Moyes admitted that it's a serious consideration ahead of the game at the Britannia on Tuesday evening.
"I think the way Stoke play, there are things you have to do to try and combat the way they play," he observed.
"But I think every team will go and play their own game, we certainly will.
"When you look at the opposition you always look to see what they do and try to make sure you can deal with it. You just go out and play and try and get the points."