On Tuesday evening, Everton take on Sunderland for the second time in 10 days.
Then, less than a fortnight later, comes a fourth meeting of the season as the Black Cats visit Goodison Park in league action.
With both matches between the sides this campaign resulting in 1-1 draws, there has been nothing to separate them so far. In fact, the two teams are only kept apart in the Premier League table by goal difference.
It comes with the territory of cup competitions, but tonight's quarter-final replay differs from the three other encounters - tonight one side must emerge victorious.
To preview the game at the Stadium of Light, evertonfc.com looks back at all of the Toffees' previous encounters with the Wearsiders in the FA Cup...
To find the very first game between the two sides in the competition, you have to go all the way back to January 17, 1891.
In the opening round, the Black Cats - who had joined the Football League at the start of the season - ran out 1-0 winners at their Newcastle Road stadium.
The clubs met again on February 19, 1910. This time the Blues came out on top with Harry Makepeace and Alex 'Sandy' Young grabbing the goals in a 2-0 third round win at Goodison.
Fifteen years passed until the two were drawn together again when January 31, 1925 brought a second round stalemate, the game ending in a goalless draw at Roker Park.
The Toffees took the tie back to Merseyside four days later and won 2-1, with Edgar Chadwick and Bobby Irvine working their way on to the scoresheet.
A full decade went by before the sides were paired together in a fourth round meeting on January 26, 1935. Once more the sides could not be separated at the first attempt, James Cunliffe netting Everton's strike in a 1-1 draw.
The Blues would again prevail at home, however, as Goodison witnessed a classic 90 minutes. Jimmy Coulter bagged a hat-trick, Albert Geldard a brace and Alex Stevenson completed a sensational 6-4 scoreline.
January 22, 1938 saw a fourth round 1-0 defeat at home for the Toffees, before a 20-year gap between cup meetings ensued.
Forcing a 2-2 away draw thanks to a pair of goals from Dave Hickson on January 4, 1958, Everton completed the task of getting through to the fourth round four days later with two strikes from Jack Keeley and another from Hickson setting up a 3-1 win.
The sides met again at Goodison the very next year on January 10, 1959, with Everton this time getting the job done in style. The prolific Hickson grabbed another two goals, with Jimmy Harris and Eddie Thomas adding to a comprehensive 4-0 scoreline.
But five years later, on February 15, 1964, the Mackems would get revenge. Harris scored again, but Sunderland prevailed 3-1 at Roker Park, easing themselves in to round six in the process.
The famous footballing year of 1966 saw Everton lift the FA Cup for the third time and on January 22, there was one of many happy cup days for the Blues at Goodison as Alex Young, Derek Temple and Fred Pickering all netted in a 3-0 third round win.
The most recent Sunderland cup win against Everton came on January 10, 1979, when a goal from midfielder Martin Dobson proved too little to prevent a 2-1 away defeat at the third round stage.
And that brings you up to the latest meeting of the two sides before this season's competition - a 3-0 win for David Moyes' men on January 29, 2005. James McFadden, James Beattie and Tim Cahill all found the net as Goodison Park joyfully witnessed the hosts march into round five at a canter.
Tonight will see the latest victor of these battles progress to the semi-finals and a mouthwatering day out at Wembley. Liverpool await.