Everton's home fixture against Arsenal will now take place on Wednesday 21 March (kick off 8pm).
The match was originally scheduled for Saturday 17 March but has been moved due to Everton's involvement in the sixth round of the FA Cup.
The game will not be televised.
David Moyes' men will be hoping to record a first win over the Gunners since Andrew Johnson scored the only goal at Goodison Park in March 2007.
The Blues suffered a 1-0 defeat to Arsenal at Emirates Stadium back in December.
The meeting will be the 197th between the two teams.