Tony Hibbert will captain Everton against BATE Borisov as he takes the Club record for the most appearances in Europe.
The Europa League clash at Goodison will be his 20th outing for the Blues putting him above the likes of Colin Harvey and Brian Labone in the list.
Leon Osman returns from the foot injury that has ruled him out since October. David Moyes though doesn't expect him to manage a full 90 minutes.
"He is not ready to play but we are pushing him to up his fitness," explained the manager in his pre-match press briefing.
"If we can get him to play 60 minutes (that is our target) but he's had no football training recently so I can't ask too much of him."
The Blues manager will also rest Tim Howard, replacing the keeper with Carlo Nash while also fielding a young squad. It will be Nash's first senior start since arriving at Everton in the summer of 2008.
With qualification to the last 32 of the competition already secured, Moyes wants to give some of the fringe members of the squad a chance to impress.
"I want them to enjoy it but they must step up," he added. "That is what it's all about when you are a youngster in a squad.
"You move from the youth set up to the reserves then the first team. It will be a good chance for us to see who will be the players of the future."
Everton (from): Nash, Coleman, Duffy, Hibbert (c), Bidwell, Osman, Forshaw, Baxter, Rodwell, Yakubu, Agard, Cahill, Howard, Baines, Bilyaletdinov, Pienaar, Fellaini, Jo, Saha, Yakubu, Akpan, Mustafi, McCarten, Garbutt.