Manchester City v Everton
Roberto Martinez is hoping Darron Gibson and Kevin Mirallas will shake off injuries to be available for the game at Manchester City on Saturday.
Gibson's knee and Mirallas' ankle are the primary injury concerns for the Blues boss.
Mirallas twisted his ankle during the win over Newcastle on Monday, a game which Gibson missed because of a recurrence of his knee problem.
The Etihad Stadium clash could come too soon for Steven Pienaar, while Gareth Barry is ineligible and Antolin Alcaraz is still around a month away from a return.
City, meanwhile, welcomed back midfield maestro David Silva on Wednesday evening, but former Blue Jack Rodwell (muscle strain) and Martin Demichelis (knee) are out of contention.
City have blown hot and cold so far this term under new manager Manuel Pellegrini.
Rampant victories over the likes of Newcastle United on the opening day and a 4-1 demolition of rivals Manchester United have been punctuated by 3-2 defeats to Cardiff City and Aston Villa, while their midweek Champions League exertions ended in a comprehensive 3-1 home loss to Bayern Munich.
Everton go into the clash as the only unbeaten side in the Barclays Premier League.
The Toffees will be aiming to pick up their fourth successive league win and second in a row on the road following the victories over Chelsea, West Ham United and Newcastle.
Everton maintained their remarkable recent record against the Citizens with a sterling 2-0 win at Goodison Park in March 2013.
Leon Osman's long-range beauty found the top corner of Joe Hart's net before Nikica Jelavic scored a memorable - albeit deflected - last-minute strike to send the Toffees faithful wild and put a further dent in the Mancunians' fading title hopes.
Tickets to Everton's game at Manchester City are sold out, but places are still available for the away match screening at Goodison Park. Click here for more details.
Supporters heading to the Etihad Stadium should be aware that the Super League Grand Final between Warrington Wolves and Wigan Warriors is being held at Old Trafford from 6pm. Northern Rail have advised that fans may notice train services are busier than normal.
Please bear this in mind when making your way out of Manchester on Saturday afternoon.