Manchester City v Everton
David Moyes shuffled his pack for the Carling Cup third round victory over West Brom on Wednesday but the likes of Tim Howard, Sylvain Distin and Leon Osman are likely to return for the Blues.
Victor Anichebe remains sidelined with a groin injury.
Manchester City almost made a host of changes as they dumped holders Birmingham out of the Carling Cup, with Owen Hargreaves and Mario Balotelli securing a 2-0 win.
Strike pairing Edin Dzeko and Sergio Aguero have combined for 15 goals already this season and should return for City up-front.
Between the two sides Everton and Manchester City have lost just one of 14 games in all competitions this season, that being the Blues opening day defeat to QPR at Goodison Park.
This will be only Everton's second away game in seven matches so far this term, they won the other won 1-0 against Blackburn Rovers last month.
Manchester City's perfect start to the Premier League season was ended at Craven Cottage last weekend when they let a two goal lead slip to draw 2-2 with Fulham.
1. The Toffees will be chasing an away win in the league for the fifth successive season against Manchester City, this feat has been achieved only once before by Everton – we won matches in seven successive seasons at Anfield from 1908-1915.
2. The five away league wins at Manchester City are the most against one side in the Moyes’ era.
3. There has not been a draw in this fixture since October 1985, the 18 matches at City since have seen nine wins apiece for the two sides.
4. Tim Howard should reach 150 successive league matches for the Blues on Saturday, making him only the second Everton player to achieve that notable feat. The legendary Neville Southall made 212 successive league appearances from 1987-1993.
5. Phil Neville requires one more appearance to reach 200 in the Premier League for Everton, the club skipper actually made his league debut for Manchester United against City 16 years ago.
EVERTON 2-1 MANCHESTER CITY (Saturday 7 May 2011). Everton produced a superb second half performance to come from behind to beat Manchester City at Goodison Park in May. Yaya Toure put the visitors ahead just before the half hour mark but Everton were all over Roberto Mancini's side after the break and Sylvain Distin headed level against his former club, before Leon Osman rose majestically above Vincent Kompany to score what proved to be the winner.
EVERTON 2-0 MANCHESTER CITY (Saturday 16 January 2010). Two set pieces helped Everton to victory over Manchester City in January 2010 on an evening where they fashioned a host of opportunities from open play and the margin for victory could have been far greater. Steven Pienaar curled in a low free kick to put the Blues ahead and then Louis Saha scored a penalty to make it 2-0. Marouane Fellaini and Tim Cahill both hit the woodwork for Everton, but the match will be remembered for Fellaini's pirouette past Craig Bellamy.
After failing to find a goalkeeper that had played for both West Brom and Everton, we're back on form this week and have managed to name a full former Everton and Manchester XI.
Carlo Nash would play in goal behind a defence of Richard Dunne, Andy Hinchcliffe and current players Sylvain Distin and Joleon Lescott.
The midfield three is a trio of Peters with messrs Beardsley, Reid and Beagrie all getting the nod.
Up-front would be Jo, Adrian Heath and Joe Royle, who has played and managed for both clubs.
The likes of Bobby Mimms, Terry Phelan and Michael Ball would all be on the bench.
Tickets are still available for the trip to Etihad Stadium on Saturday call the box office on 0871 663 1878 for more details.