Benfica v Everton
Everton's much-depleted squad suffered a painful night in Portugal, going down 5-0 to Benfica.
Benfica had no such problems and they demonstrated their attacking progress in the seven minutes directly after half time.
An Oscar Cardozo brace and a Luisao header added to Javier Saviola's first half effort, with the diminutive striker adding a fifth late on.
Home skipper Luisao was often a threat at set pieces and he had an effort blocked by Sylvain Distin inside the first minute before glancing another effort wide a couple of minutes later.
But soon Las Aguilas were ahead when ex-Real Madrid and Barcelona forward Saviola volleyed home in the 14th minute.
Everton tried to retaliate and from the restart Jo shot straight at Julio Cesar in the Benfica goal.
Stand-in skipper Tim Cahill headed a corner over on the half hour and then a first-time Diniyar Bilyaletdinov left foot volley whistled over the bar.
Anther effort from the same player was further off target moments later but at least Everton were getting sights at goal.
But after the break Everton's hopes at getting back on level terms were extinguished with three quick-fire goals.
Just a minute into the second half Oscar Cardozo converted a Saviola centre to double the lead.
And a barely 60 seconds later it was three as Benfica again surged down the left and Cardozo, this time with his head, was in the right place to finish with ease.
The explosive beginning to the half continued in the 53nd minute when Luisao headed in Pablo Aimar's corner.
And still the Portuguese pressed; Angel Di Maria hit the bar with a curling effort and then he fired another effort straight at Tim Howard.
David Moyes introduced Louis Saha on the hour mark but the action was at the other end as Howard denied Cardozo his hat-trick with a good low save.
There were 20 minutes of action for youngster Jose Baxter but it was fellow sub Saha who sent an acrobatic effort off the post with 12 minutes left.
But Everton's misery was compounded in the 83rd minute when Howard misjudged a through-ball and Di Maria laid it on a plate for Saviola's second and Benfica's fifth.
The result means Everton now sit in second place in the group, still well-placed with two home games to come.