Marco Silva confirmed Everton are still without defenders Phil Jagielka and Leighton Baines in his pre-match press conference.
The Blues boss also admitted Yerry Mina is a doubt for the trip to Hertfordshire.
For the Hornets, influential midfielder Roberto Pereyra and striker Isaac Success (both hamstring) may again miss out but defender Kiko Fermenia (hamstring) will be assessed ahead of kick off.
Midfielder Abdoulaye Doucoure could also feature after shaking off a knee injury but Sebastien Prodl remains a long-term absentee.
Everton will be looking to replicate the performance if not the result from Wednesday night’s 2-0 defeat to Manchester City.
The Blues displayed plenty of aggression and desire against the title-chasers but were beaten by goals from Aymeric Laporte and Gabriel Jesus.
Watford, meanwhile, are on a run of four wins in their last 10, although they have lost just twice in that time.
Their most recent outing was a 0-0 draw at Brighton’s Amex Stadium last weekend.
1. Richarlison: 10 (seventh in PL)
2. Gylfi Sigurdsson: 9
3. Dominic Calvert-Lewin: 4
1. Idrissa Gana Gueye: 88 (third in PL)
2. Lucas Digne: 49
3. Gylfi Sigurdsson: 38
1. Gylfi Sigurdsson: 62 (ninth in PL)
2. Richarlison: 55 (10th in PL)
3. Theo Walcott: 29
1. Roberto Pereyra: 6
2. Troy Deeney: 5
3. Five players
1. Etienne Capoue: 57
2. Jose Holebas: 51
3. Abdoulaye Doucoure: 47
1. Roberto Pereyra: 46
2. Troy Deeney: 44
3. Abdoulaye Doucoure: 35
FACTS AND FIGURES
Everton and Watford have faced each other 27 times previously.
The Blues have picked up 19 wins in that time, losing on just four occasions.
Games between the two clubs tend to be high-scoring affairs – the most recent meeting being a 2-2 draw at Goodison Park back in December.
Everton left Vicarage Road with a 4-4 draw in February 1984 and, just a few months later, needed to net five times to edge a nine-goal thriller in Hertfordshire, with Adrian Heath scoring twice.
The Blues also rattled in four goals in successive home games against the Hornets in 1985, before again doing so in an April 2000 clash at Goodison.
KEY MAN: Ben Foster
One of the contributing factors to Watford’s rise to eighth in the Premier League table is the form of goalkeeper Ben Foster.
Back for a second spell at a club where he spent two seasons on loan while on the books of Manchester United, the 36-year-old former England man has sparkled between the sticks at Vicarage Road.
His 78 saves this season put him fourth on the list of Premier League glovesmen behind only Lukasz Fabianksi, David De Gea and Neil Etheridge.
"He has an amazing character and ambition, and his experience is very good for us," said Hornets boss Javi Gracia after Foster played a key part in his side’s 0-0 draw at Brighton last time out.
“It was a special performance. He is a very important player for us.”
MAN IN THE MIDDLE: Lee Probert
Wiltshire resident Lee Probert takes charge of his 21st game of the season when he officiates at Vicarage Road on Saturday.
He has handed out 68 yellow cards and six reds so far this campaign.
Two of those reds were shown in his last Everton game, the 2-2 draw at Bournemouth back in August. First Blues forward Richarlison was dismissed on 41 minutes before Cherries defender Adam Smith also went off after the break.